Author

Leighton S. Lee

University at Buffalo, State University of New York

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew T. LombardoiD· 2 shared Christine E. Schaner TooleyiD· 2 shared Emma C. Murray· 2 shared Gillian M. Hodge· 2 shared Namya ManojiD· 2 shared Shane Fraher· 2 shared Yongho BaeiD· 2 shared Cameron A.R. Mitchell· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersCell Biology

Andrew T. LombardoORCID

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2 papers

Recent·Most cited

Myosin-9b Controls Epithelial Brush Border Architecture through Motility-Dependent RhoA Signaling

Emma C. Murray, Namya Manoj, Lynn M. Ziegler, Gillian M. Hodge, Shane Fraher, Leighton S. Lee, Lucas Code, Steven A. Lewis, Christine E. Schaner Tooley, Yongho Bae, John Konen, Jonathan Bard, Andrew T. Lombardo

This study identifies Myo9b's role in regulating epithelial brush border microvilli through RhoA signaling and shows that a disease variant disrupts microvilli formation in human cells.

bioRxiv · Sep 11, 2026 · PreprintCell Biology

The Rho effector ARHGAP18 coordinates a Hippo pathway feedback loop through YAP and Merlin to regulate the cytoskeleton and epithelial cell polarity.

Emma C. Murray, Gillian M. Hodge, Khanh Pham, Shane Fraher, Leighton S. Lee, Cameron A.R. Mitchell, Namya Manoj, Christine E. Schaner Tooley, Yongho Bae, Andrew T. Lombardo

This study identifies ARHGAP18 as a RhoA effector that forms a complex with YAP to coordinate Hippo and Rho pathways in regulating actin cytoskeleton and epithelial polarity.

Molecular Biology of the Cell · May 13, 2026Peer-reviewedCell Biology