Author

Steven M. Coyne

Boston Children's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Assay:multiome· 1

Frequent Co-Authors

Daniel E. BaueriD· 2 shared Akiko ShimamuraiD· 1 shared Arish N ShahiD· 1 shared Ashley M. GutierreziD· 1 shared Avik Choudhuri· 1 shared Chunjie YuiD· 1 shared David S. Wiley· 1 shared Divya S. VinjamuriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenetics

Daniel E. BauerORCID

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2 papers

Recent·Most cited

Direct and indirect regulation of fetal globin transcript by RNA-binding protein IGF2BP1

Steven M. Coyne, Gue-Ho Hwang, Ting Wu, Mir Ahamed Hossain, Divya S. Vinjamur, M M Starrs, Jing Zeng, Felicia Andresen, Ashley M. Gutierrez, Akiko Shimamura, Daniel E. Bauer

This study identifies IGF2BP1 as a direct and indirect regulator of fetal globin transcripts through m6A modification and interaction with HIC2 and BCL11A.

Blood · Jun 24, 2026Peer-reviewedGenetics

RNA methylation controls stress granule formation and function during erythropoiesis

Rajesh D. Gunage, Shuibin Lin, David S. Wiley, Avik Choudhuri, Mackenzie Smith, Tianxiao Han, Arish N Shah, Steven M. Coyne, Katherine Koczirka, Kenny Zhi Ming Chen, Chunjie Yu, Kyle D. Drake, Xin Yang, Song P. Yang, Yi Zhou, , Leonard Ira Zon

This study shows that RNA methylation, specifically m6A, regulates stress granule formation and function during erythropoiesis by modulating ATXN2 expression and RNA translation.

bioRxiv · Nov 7, 2024 · PreprintCell Biology