Author
Yi Zhou
Boston Children's HospitalORCID 0000-0003-0935-1635Unclaimed ORCID profile · follow to get notified of new preprints
Additional preprints under this name without ORCID
Biology Disciplines
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2017-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 29 mutual co-author linksMutual co-authors in cluster
8 papers
Recent·Most cited
- Cancer BiologybioRxivPreprint
- Cancer BiologyCellPeer-reviewed
Craters on the melanoma surface facilitate tumor-immune interactions and demonstrate pathologic response to checkpoint blockade in humans
Aya Ludin, Georgia L. Stirtz, Asaf Tal…·Leonard Ira Zon
The paper identifies crater-shaped structures in melanoma that enhance immune response to checkpoint blockade therapy in humans and zebrafish.
- Cell BiologybioRxivPreprint
RNA methylation controls stress granule formation and function during erythropoiesis
Rajesh D. Gunage, Shuibin Lin, David S. Wiley…·Leonard Ira Zon
This study shows that RNA methylation, specifically m6A, regulates stress granule formation and function during erythropoiesis by modulating ATXN2 expression and RNA translation.
1 citation - Developmental BiologyDevelopmental CellPeer-reviewed
Transcription factor induction of vascular blood stem cell niches in vivo
Elliott J. Hagedorn, Julie R. Perlin, Rebecca J. Freeman…·Leonard Ira Zon
This study identifies transcription factors that induce vascular blood stem cell niches in vivo, enabling synthetic niche generation and potential therapeutic applications.
19 citations - Developmental BiologyeLifePeer-reviewed
Niche signals regulate continuous transcriptional states in hematopoietic stem cells
Eva Maria Fast, Audrey Sporrij, Margot E. Manning…·Leonard Ira Zon
The paper identifies six HSC states and shows niche perturbations induce rapid transitions between them, revealing HSC-specific molecular signatures and chromatin features related to regenerative potential.
- Developmental BiologyProceedings of the National Academy of SciencesPeer-reviewed
Specific Oxylipins Enhance Vertebrate Hematopoiesis via the Receptor GPR132
Jamie L. Lahvic, Michelle Ammerman, Pulin Li…·Leonard Ira Zon
The paper identifies GPR132 as a specific receptor for certain oxylipins that enhance hematopoiesis in vertebrates, using bioinformatics and functional assays.
- GeneticsPLoS GeneticsPeer-reviewed
RNA helicase, DDX27 regulates skeletal muscle growth and regeneration by modulation of translational processes
Alexis H. Bennett, Marie-Françoise O’Donohue, Stacey R. Gundry…·Vandana Gupta
This study identifies DDX27 as a regulator of skeletal muscle growth and regeneration by modulating translational processes and ribosome biogenesis in zebrafish.
47 citations - GeneticsbioRxivPreprint
Zebrafish models for human ALA-dehydratase-deficient porphyria (ADP) and hereditary coproporphyria (HCP) generated with TALEN and CRISPR-Cas9
Shuqing Zhang, Jiao Meng, Zhijie Niu…·Han Wang
This paper generates zebrafish models for human ALA-dehydratase-deficient porphyria and hereditary coproporphyria using TALEN and CRISPR-Cas9, revealing phenotypes similar to human diseases.
DOI 10.1101/109553