Author

Mackenzie Smith

Loyola University Chicago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Bioinformatics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:imaging· 2 Organism:mouse· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

Rocco G. GogliottiiD· 2 shared Alan RuttenbergiD· 1 shared Alexander BartnikiD· 1 shared Alexander D. DiehliD· 1 shared Amanda M. VanderplowiD· 1 shared Arish N ShahiD· 1 shared Avik Choudhuri· 1 shared Chunjie YuiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersNeuroscience

Rocco G. GogliottiORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Profiling metabotropic glutamate receptor 7 expression in Rett syndrome: consequences for pharmacotherapy

Sheryl Anne D. Vermudez, Geanne A. Freitas, Mackenzie Smith, Rocco G. Gogliotti, Colleen Marie Niswender

The paper investigates mGlu7 expression in Rett syndrome and shows that mGlu7 PAMs can reduce apneas in RTT patients.

Neuroscience · Jan 30, 2026Peer-reviewedNeuroscience

Potentiation of the M1 muscarinic acetylcholine receptor normalizes neuronal activation patterns and improves apnea severity in Mecp2+/- mice

Mackenzie Smith, Grace E. Dodis, Amanda M. Vanderplow, Sonia Gonzalez, Yewon Rhee, Karie Elizabeth Scrogin, Rocco G. Gogliotti

This study shows that M1 receptor potentiation reduces apnea severity in Mecp2+/- mice by normalizing brainstem hyperactivity and altering neuronal activation patterns.

Neurobiology of Disease · Feb 26, 2025Peer-reviewedNeuroscience

RNA methylation controls stress granule formation and function during erythropoiesis

Rajesh D. Gunage, Shuibin Lin, David S. Wiley, Avik Choudhuri, Mackenzie Smith, Tianxiao Han, Arish N Shah, Steven M. Coyne, Katherine Koczirka, Kenny Zhi Ming Chen, Chunjie Yu, Kyle D. Drake, Xin Yang, Song P. Yang, Yi Zhou, , Leonard Ira Zon

This study shows that RNA methylation, specifically m6A, regulates stress granule formation and function during erythropoiesis by modulating ATXN2 expression and RNA translation.

bioRxiv · Nov 7, 2024 · PreprintCell Biology

MRIO: The Magnetic Resonance Imaging Acquisition and Analysis Ontology

Alexander Bartnik, Lucas M. Serra, Mackenzie Smith, William D. Duncan, Lauren Wishnie, Alan Ruttenberg, Michael G. Dwyer, Alexander D. Diehl

The paper introduces MRIO, an ontology for MRI data acquisition and analysis to standardize and improve reproducibility in neuroimaging research.

Neuroinformatics · May 19, 2024Peer-reviewedBioinformatics