Leiomodin 2 functions as a processive pointed-end elongator of actin filaments
Sudipta Biswas, Tania M. Larrinaga, Sandeep Choubey, Carol C. Gregorio, Shashank Shekhar
This study identifies Leiomodin 2 as a processive actin polymerase that elongates pointed ends of actin filaments, linking its dysfunction to dilated cardiomyopathy.
bioRxiv · May 7, 2026 · PreprintBiochemistry