Author

Sung-Yeon Lee

Macrogen (South Korea)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Ai CheniD· 1 shared Beomjoon JoiD· 1 shared Biyun ZhuiD· 1 shared Dan MuiD· 1 shared Dasom Lee· 1 shared Eunsoo Jang· 1 shared Hansol Koo· 1 shared Heeyoung SeokiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenetics

Ai ChenORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Empirical optimization of dual-sgRNA design for in vivo CRISPR/Cas9-mediated exon deletion in mice

Sung-Yeon Lee, Seongwon Ma, Sangjun Davie Jeon, Hyoju Kim, Beomjoon Jo, Seung-Hoon Han, Eunsoo Jang, Jimin Lee, Yong-Kyu Lee, Dasom Lee

This study develops an in vivo-trained model to predict dual-sgRNA efficiency for exon deletion in mice, achieving an AUC of 0.759.

Computational and Structural Biotechnology Journal · Jan 1, 2026Peer-reviewedBioinformatics

PAM-flexible adenine base editing rescues hearing loss in a humanized MPZL2 mouse model harboring an East Asian founder mutation

Shao Wei Hu, Sohyang Jeong, Luoying Jiang, Hansol Koo, Zijing Wang, Won Hoon Choi, Biyun Zhu, Heeyoung Seok, Yi Zhou, Min Gu Kim, Dan Mu, Huixia Guo, Ziyi Zhou, Sung Ho Jung, Yingting Zhang, , Yilai Shu

This study uses base editing to correct a mutation causing hearing loss in a humanized mouse model, restoring hearing function and gene expression.

bioRxiv · Oct 29, 2024 · PreprintGenetics