A histidine switch controls the pH-responsive self-assembly of a helical protein filament
Swasti Rawal, Stefan Bohn, Maria Bacia‐Verloop, Benjamin M. R. Bourgeois, Đesika Kolarić, Dagmar Kolb, Tea Pavkov‐Keller, Iva Pritišanac, Tobias Madl, Ambroise Desfosses, T. Reid Alderson
The paper identifies a histidine switch that regulates pH-responsive self-assembly of a helical protein filament through electrostatic interactions.
bioRxiv · Jun 17, 2026 · PreprintBiophysics