Benjamin M. R. Bourgeois

A metabolic perspective on eIF1A and eIF3B inhibition as a potential therapeutic strategy in psoriasis

This study investigates the metabolic effects of eIF1A and eIF3B inhibition in psoriasis models, finding context-dependent metabolic changes and therapeutic benefits.

A histidine switch controls the pH-responsive self-assembly of a helical protein filament

The paper identifies a histidine switch that regulates pH-responsive self-assembly of a helical protein filament through electrostatic interactions.

TDP-43 self-assembly is regulated by its disordered NLS-region

This study shows that the disordered NLS-region of TDP-43 is essential for its self-assembly across multiple scales, with a minimal mutation preserving condensation while others reduce it.

The sequence context of RG/RGG motifs determines condensate formation, transportin-1 binding and chaperoning

The paper investigates how sequence context of RG/RGG motifs influences condensate formation, transportin-1 binding, and chaperoning using bioinformatics and experimental analysis.