Greatwall depletion from Xenopus oocytes reveals a key role of the cyclin B/CDK1-PP2A-B55 balance in the coordination of meiotic events
Sylvain Roque, Celia Ben Choug, Cédric Hassen‐Khodja, Suzanne Vigneron, Véronique Legros, Guillaume Chevreux, Benjamin Lacroix, Anna Castro, Thierry Lorca
This study shows that Greatwall kinase coordinates meiotic divisions by regulating PP2A-B55, which controls APC/C and Mos/MAPK pathways in Xenopus oocytes.
Nature Communications · May 13, 2026Peer-reviewedBiochemistry