Author

T. Alarcon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Research Focus:phylogenetics / evolution· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

H. M. Byrne· 2 shared P. K. Maini· 2 shared A. Beardo· 1 shared A. V. Ponce Bobadilla· 1 shared B. Markelc· 1 shared B. Martinez-Gonzalez· 1 shared B. Pascoe· 1 shared D. Falush· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCancer Biology

H. M. Byrne

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Repeated out-of-Africa expansions of Helicobacter pylori driven by replacement of deleterious mutations

H. A. Thorpe, E. Tourrette, K. Yahara, F. F. Vale, S. Liu, M. Oleastro, T. Alarcon, T. Perets, S. Latifi-Navid, Y. Yamaoka, B. Martinez-Gonzalez, I. Karayiannis, T. Karamitros, D. Sgouras, W. Elamin, , D. Falush

This study shows H. pylori has spread repeatedly from Africa by replacing strains with deleterious mutations through migration and selection.

bioRxiv · Jun 5, 2021Evolutionary Biology

Abnormal morphology biases haematocrit distribution in tumour vasculature and contributes to heterogeneity in tissue oxygenation

M. O. Bernabeu, J. Kory, J. A. Grogan, B. Markelc, A. Beardo, M. d'Avezac, R. Enjalbert, J. Kaeppler, N. Daly, J. Hetherington, T. Krueger, P. K. Maini, J. M. Pitt-Francis, R. J. Muschel, T. Alarcon, H. M. Byrne

The paper investigates how abnormal vascular morphology affects haematocrit distribution and tissue oxygenation in tumours, introducing a metric λ to monitor anti-angiogenic treatment efficacy.

bioRxiv · Aug 28, 2020 · PreprintCancer Biology

Age-structure as key to delayed logistic proliferation of scratch assays

A. V. Ponce Bobadilla, T. Carraro, H. M. Byrne, P. K. Maini, T. Alarcon

This paper introduces a non-linear age-structured population model to explain the two-phase proliferation observed in scratch assays, showing that resource concentration regulates the transition between phases.

bioRxiv · Feb 4, 2019Cell Biology