K. Yahara

In vitro activity of cefiderocol against carbapenemase-producing and meropenem-nonsusceptible gram-negative bacteria collected in the Japan Antimicrobial Resistant Bacterial Surveillance (JARBS-GNR)

This study evaluates the in vitro activity of cefiderocol against carbapenemase-producing and meropenem-nonsusceptible gram-negative bacteria from Japan, showing high susceptibility rates compared to other antibiotics.

Nationwide genome surveillance of carbapenem-resistant Pseudomonas aeruginosa in Japan

This study analyzes genome sequences and antimicrobial resistance patterns of carbapenem-resistant Pseudomonas aeruginosa isolates from Japan, revealing genetic diversity and lower multidrug resistance prevalence compared to other regions.

Contrasting genes conferring short and long-term biofilm adaptation in Listeria

This study identifies 273 genes associated with biofilm formation in Listeria monocytogenes through GWAS and 220 genes through RNAseq, finding fewer overlaps than expected, suggesting distinct evolutionary adaptation mechanisms.

Host ecology regulates interspecies recombination in bacteria of the genus Campylobacter

The paper quantifies horizontal gene transfer (HGT) between Campylobacter species with different host ecologies, showing cohabitation in the same host increases HGT by 6-fold.

Repeated out-of-Africa expansions of Helicobacter pylori driven by replacement of deleterious mutations

This study shows H. pylori has spread repeatedly from Africa by replacing strains with deleterious mutations through migration and selection.

Genomic differentiation within East Asian Helicobacter pylori

This study identifies genomic differentiation in Helicobacter pylori across East Asia, linking specific SNPs to cancer risk and geographic adaptation.

A two-hit epistasis model prevents core genome disharmony in recombining bacteria

The paper shows that recombination in bacteria can overcome genomic disharmony through a two-hit epistasis model, allowing beneficial gene combinations to be reinstated in new genetic backgrounds.

Genome-wide association study of gastric cancer- and duodenal ulcer-derived Helicobacter pylori strains reveals discriminatory amino acid differences and novel oncoprotein candidates

This study uses GWAS to identify genetic variations in H. pylori strains associated with gastric cancer and duodenal ulcers, revealing amino acid differences and novel oncoprotein candidates.

On-site genomic epidemiological analysis of antimicrobial-resistant bacteria in Cambodia with portable laboratory equipment

This study uses portable lab equipment to analyze antimicrobial-resistant bacteria in Cambodia, identifying specific resistance genes and their plasmid locations.

Emergence and evolution of antimicrobial resistance genes and mutations in Neisseria gonorrhoeae

This study traces the emergence and spread of antimicrobial resistance in Neisseria gonorrhoeae by analyzing genome sequences from multiple countries and time periods, revealing recombination events and antibiotic-driven mutations.

Comparison of de-duplication methods used by WHO Global Antimicrobial Resistance Surveillance System (GLASS) and Japan Nosocomial Infections Surveillance (JANIS) in the surveillance of antimicrobial resistance

This study compares de-duplication methods from WHO GLASS and JANIS systems for AMR surveillance, finding small differences in patient counts and resistance percentages for E. coli.

Plasmid analysis of NDM metallo-β-lactamase-producing Enterobacterales isolated in Vietnam

The paper characterizes blaNDM-1-carrying plasmids in Vietnamese Enterobacterales isolates, identifying horizontal plasmid transfer and resistance gene co-occurrence.

Long-read shotgun metagenome sequencing using PromethION uncovers novel bacteriophages, their abundance, and interaction with host bacterial immunity in the oral microbiota

This study uses long-read metagenomic sequencing to identify novel bacteriophages and their interactions with host immunity in the oral microbiota.