Author

T. Apablaza

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Guequen· 2 shared C. A. Flores· 2 shared L. Delpiano· 2 shared M. Gray· 2 shared S. Villanueva· 2 shared A. Mansilla· 1 shared A. R. Philp· 1 shared B. D. Baxter· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersPhysiology

A. Guequen

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2 papers

Recent·Most cited

Airway succinate chemosensing induces CFTR-dependent anion secretion and mucus clearance which is impaired in cystic fibrosis.

T. Apablaza, M. Barros-Poblete, L. Delpiano, S. Villanueva, A. Guequen, B. Tapia-Balladares, I. J. Haq, F. Tribinos, S. Hernandez-Rivas, B. Verdon, M. G. Biggart, Y. Sanchez, C. Ward, B. D. Baxter, D. Restrepo, , C. A. Flores

bioRxiv · Mar 26, 2024 · PreprintPhysiology

Inhibition of the sodium-dependent HCO3 -transporter SLC4A4, produces a cystic fibrosis-like airway disease phenotype.

V. Saint-Criq, A. Guequen, A. R. Philp, S. Villanueva, T. Apablaza, I. Fernandez-Moncada, A. Mansilla, L. Delpiano, I. Ruminot, C. Carrasco, M. Gray, C. A. Flores

This study shows that inhibiting SLC4A4, a sodium-dependent bicarbonate cotransporter, in airway epithelial cells causes a CF-like phenotype with mucus accumulation and reduced mucociliary clearance.

bioRxiv · Dec 14, 2021Physiology