Author

T. Burns

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1

Frequent Co-Authors

C. Riviere-Cazaux· 3 shared C. Shaw· 3 shared M. R. Khan· 3 shared L. Strother· 2 shared S. Otto· 2 shared A. E. Warrington· 1 shared A. Howard· 1 shared B. L. Carlson· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersBioengineering

C. Riviere-Cazaux

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Convection-enhanced diffusion and directed withdrawal of methylene blue in agarose hydrogel using finite element analyses

C. Shaw, K. Hossain, C. Riviere-Cazaux, T. Burns, M. R. Khan

This study uses finite element analysis to simulate convection-enhanced drug delivery in agarose hydrogels, showing how directed flow improves drug distribution and concentration control.

bioRxiv · Oct 27, 2022 · PreprintBioengineering

In Silico, Brain Mesh Platform for Computing Topographic Dependent Internal Facets

C. Shaw, C. Riviere-Cazaux, D. Obrochta, S. Otto, L. Ray, L. Strother, T. Burns, M. R. Khan

The paper develops a brain modeling platform using patient MRI data to simulate drug dispersal and fluid flow in healthy and diseased brains, focusing on glioblastoma.

bioRxiv · Oct 27, 2022 · PreprintBioengineering

MRI-to-Synthetic 3D Gel Brain: Proof-of-Concept Fabrication For Intra-Parenchymal Diffusion Studies

L. M. Ray, C. Shaw, S. Otto, C. Riviere-Cazaux, L. Strother, T. Burns, M. R. Khan

This paper demonstrates a method to create synthetic 3D gel brains from MRI data to study intra-parenchymal diffusion, showing improved representation of diffusion profiles compared to simple gel models.

bioRxiv · Oct 27, 2022 · PreprintBioengineering

Selective Vulnerability of Senescent Glioblastoma Cells to Bcl-XL Inhibition

M. Rahman, I. E. Olson, M. Mansour, L. P. Carlstrom, R. Sutiwisesak, R. Saber, K. Rajani, A. E. Warrington, A. Howard, M. Schroeder, S. Chen, P. A. Decker, Y. Zhu, I. F. Parney, S. Burma, , E. F. Sananikone

This study identifies Bcl-XL inhibition as a selective vulnerability of senescent glioblastoma cells following radiation or TMZ treatment.

bioRxiv · Jun 3, 2020Cancer Biology

Radiation Induced Metabolic Alterations Associate with Tumor Aggressiveness and Poor Outcome in Glioblastoma

K. Gupta, I. Vuckovic, S. Zhang, Y. Xiong, B. L. Carlson, J. Jacobs, I. Olson, X.-M. Petterson, S. I. Macura, J. Sarkaria, T. Burns

This study shows that prior radiation therapy promotes tumor aggressiveness in glioblastoma by inducing metabolic changes that create a protumorigenic microenvironment.

bioRxiv · Feb 4, 2020Cancer Biology