Author

R. T. Bronson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:mouse· 5 Research Focus:cancer & tumor microenvironment· 3 Research Focus:cell type annotation· 3 Research Focus:clustering· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:differential expression· 1

Frequent Co-Authors

L. M. Selfors· 2 shared A. Aktipis· 1 shared A. Bhutkar· 1 shared A. Chimento· 1 shared A. F. Hazel· 1 shared A. Jin· 1 shared A. K. Challa· 1 shared A. M. Cruz· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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2 shared papersBiochemistry

L. M. Selfors

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Ketogenic diet as a metabolic vehicle for enhancing the therapeutic efficacy of mebendazole and devimistat in preclinical high-grade gliomas grown in juvenile mice

P. Mukherjee, J. Maurer, S. A. Stopka, B. Greenwood, J. J. A. Henao, S. Karmacharya, A. Chimento, N. Ta, D. C. Lee, T. Duraj, R. T. Bronson, M. A. Kiebish, T. N. Seyfried

This study shows that combining a ketogenic diet with mebendazole or devimistat improves therapeutic outcomes in preclinical high-grade glioma models in juvenile mice.

bioRxiv · Jun 9, 2023 · PreprintCancer Biology

Glutathione supports lipid abundance in vivo

G. Asantewaa, E. T. Tuttle, N. P. Ward, Y. P. Kang, Y. Kim, M. E. Kavanagh, N. Girnius, Y. Chen, R. Duncan, K. Rodriguez, F. Hecht, M. Zocchi, L. Smorodintsev-Schiller, T. Q. Scales, K. Taylor, , I. S. Harris

This study shows that glutathione (GSH) is essential for lipid abundance in adult tissues, particularly in the liver, by repressing NRF2.

bioRxiv · Feb 10, 2023 · PreprintBiochemistry

Clinical Viability of Magnetic Bead Implants in Muscle

C. R. Taylor, W. H. Clark, E. G. Clarrissimeaux, S. H. Yeon, M. J. Carty, S. R. Lipsitz, R. T. Bronson, T. J. Roberts, H. M. Herr

This paper evaluates the clinical viability of magnetic bead implants for real-time muscle length monitoring in animals, finding no adverse effects and supporting their potential use in human applications.

bioRxiv · Aug 1, 2022Bioengineering

Mismatch repair deficiency is not sufficient to increase tumor immunogenicity

P. M. K. Westcott, F. Muyas, O. Smith, H. Hauck, N. J. Sacks, Z. A. Ely, A. M. Jaeger, W. M. Rideout, A. Bhutkar, D. Zhang, M. C. Beytagh, D. A. Canner, R. T. Bronson, S. Naranjo, A. Jin, , T. Jacks

This study shows that MMRd in mouse tumor models does not increase immunogenicity or ICB response, due to intratumoral heterogeneity.

bioRxiv · Aug 24, 2021 · PreprintCancer Biology

Transient Commensal Clonal Interactions Can Drive Tumor Metastasis

S. Naffar-Abu Amara, H. J. Kuiken, L. M. Selfors, T. Butler, M. L. Leung, C. T. Leung, E. P. Kuhn, T. R. Kolarova, C. Hage, K. Ganesh, R. Foster, B. R. Rueda, A. Aktipis, P. T. Spellman, T. Ince, , J. S. S. Brugge

The paper shows that transient interactions between non-tumorigenic and tumorigenic clones can drive metastasis through amphiregulin-mediated mesothelial clearance.

bioRxiv · Jan 16, 2020 · PreprintCancer Biology

NF1 deficiency correlates with estrogen receptor signaling and diminished survival in breast cancer

P. S. Dischinger, E. A. Tovar, C. J. Essenburg, Z. B. Madaj, E. E. Gardner, M. Callaghan, A. N. Turner, A. K. Challa, T. Kempston, B. Eagleson, R. A. Kesterson, R. T. Bronson, M. J. Bowman, C. R. Graveel, M. R. Steensma

This study shows NF1 deficiency in breast cancer correlates with estrogen receptor signaling and poor survival, using rat models and human genomic data.

bioRxiv · Feb 27, 2018Cancer Biology