Author

T. F. Moraes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Assay:structural biology· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. Pan· 3 shared M. Shah· 2 shared A. B. Schryvers· 1 shared A. R. Davidson· 1 shared A. Zimmer· 1 shared B. Garcia· 1 shared B. Sit· 1 shared C. C. Lai· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBiochemistry

C. Pan

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Use of Epivolve phage display to generate a monoclonal antibody with opsonic activity directed against a subdominant epitope on extracellular loop 4 of Treponema pallidum BamA (TP0326)

M. Ferguson, K. N. Delgado, S. McBride, I. C. Orbe, C. J. LaVake, M. J. Caimano, Q. Mendez, T. F. Moraes, A. B. Schryvers, M. A. Moody, J. D. Radolf, M. Weiner, K. L. Hawley

This paper uses the Epivolve phage display method to generate monoclonal antibodies targeting a subdominant epitope on Treponema pallidum BamA, showing opsonic activity in macrophage assays.

bioRxiv · May 13, 2023Immunology

Prevalence of Slam-dependent hemophores in Gram-negative bacteria

T. F. Moraes, H. E. Shin, C. Pan, D. M. Curran, T. J. Bateman, D. H. Chong, D. Ng, M. Shah

The paper identifies HphAs as a new class of hemophores in Gram-negative bacteria, showing their structural similarity to hemophilin1 and dependence on Slam for secretion.

bioRxiv · Mar 29, 2023 · PreprintMicrobiology

Structural and mechanistic insight into CRISPR-Cas9 inhibition by anti-CRISPR protein AcrIIC4

S. Hwang, C. Pan, B. Garcia, A. R. Davidson, T. F. Moraes, K. L. Maxwell

This study investigates how AcrIIC4 inhibits CRISPR-Cas9 by binding to its Recognition Domain and blocking DNA cleavage through conformational changes.

bioRxiv · Jul 9, 2021Biochemistry

Actinobacillus utilizes a binding-protein dependent ABC transporter to acquire Vitamin B6

C. Pan, A. Zimmer, M. Shah, M. Huynh, C. C. Lai, B. Sit, Y. Hooda, D. Curran, T. F. Moraes

The paper identifies a Vitamin B6 uptake system in Actinobacillus using a binding-protein dependent ABC transporter, validated through structural and biochemical methods.

bioRxiv · May 1, 2020 · PreprintBiochemistry