Author

M. J. Caimano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

J. D. Radolf· 2 shared K. L. Hawley· 2 shared A. A. Grassmann· 1 shared A. Anand· 1 shared A. B. Schryvers· 1 shared A. Dey· 1 shared A. P. Chan· 1 shared A. R. Cruz· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

J. D. Radolf

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Borrelia PeptideAtlas: A proteome resource of common Borrelia burgdorferi isolates for Lyme research

P. J. Reddy, Z. Sun, H. H. Wippel, D. H. Baxter, K. E. Swearingen, D. D. Shteynberg, M. K. Midha, M. J. Caimano, K. Strle, Y. Choi, A. P. Chan, N. J. Schork, R. L. Moritz

The paper constructs a proteome resource, Borrelia PeptideAtlas, by integrating transcriptomic and proteomic data from multiple B. burgdorferi isolates to identify common proteins across infective strains.

bioRxiv · Jun 16, 2023 · PreprintBiochemistry

Use of Epivolve phage display to generate a monoclonal antibody with opsonic activity directed against a subdominant epitope on extracellular loop 4 of Treponema pallidum BamA (TP0326)

M. Ferguson, K. N. Delgado, S. McBride, I. C. Orbe, C. J. LaVake, M. J. Caimano, Q. Mendez, T. F. Moraes, A. B. Schryvers, M. A. Moody, J. D. Radolf, M. Weiner, K. L. Hawley

This paper uses the Epivolve phage display method to generate monoclonal antibodies targeting a subdominant epitope on Treponema pallidum BamA, showing opsonic activity in macrophage assays.

bioRxiv · May 13, 2023Immunology

The FUR-like regulators PerRA and PerRB integrate a complex regulatory network that promotes mammalian host-adaptation and virulence of Leptospira interrogans.

A. A. Grassmann, C. Zavala-Alvarado, E. Bettin, M. Picardeau, N. Benaroudj, M. J. Caimano

This study identifies PerRA and PerRB as key regulators in Leptospira interrogans that enhance host adaptation and virulence through complex gene regulation networks.

bioRxiv · Nov 5, 2020Microbiology

Sequence variation of rare outer membrane protein β-barrel domains in clinical strains provides insights into the evolution of Treponema pallidum subsp. pallidum, the syphilis spirochete.

S. Kumar, M. J. Caimano, A. Anand, A. Dey, K. L. Hawley, M. LeDoyt, C. La Vake, A. R. Cruz, L. G. Ramirez, L. Pastekova, I. Bezsonova, D. Smajs, J. C. Salazar, J. D. Radolf

The paper analyzes sequence variation in β-barrel domains of OMPs in TPA clinical strains, finding that genetic exchange and host selection pressures drive OMP diversity and inform vaccine strategies.

bioRxiv · May 9, 2018Microbiology