T. Ferreira

Absence of Telomerase Leads to Immune Response and Tumor Regression in Zebrafish Melanoma

This study shows that telomerase absence in zebrafish melanoma leads to tumor regression via immune response and cell cycle arrest, despite initial tumor formation.

A \"Dirty\" Footprint: Anthropogenic Soils Promote Biodiversity in Amazonian Rainforests

The paper examines soil macroinvertebrate communities in Amazonian Dark Earths (ADEs) and finds higher biodiversity and biological activity compared to adjacent soils, highlighting the impact of human activities on Amazonian ecosystems.

Environment and sex control lifespan and telomere length in wild-derived African killifish

The paper examines the relationship between telomere length, lifespan, and environmental factors in African killifish, finding sex-based differences and environmental influences on telomere length.

Polyunsaturated phospholipids increase cell resilience to mechanical constraints

The paper shows that polyunsaturated phospholipids, especially DHA, enhance muscle cell resilience to mechanical stress by promoting vacuole-like dilation in the plasma membrane.

A comprehensive study of Phospholipid fatty acid rearrangements in the early onset of the metabolic syndrome: correlations to organ dysfunction.

This study examines phospholipid fatty acid rearrangements in rats fed a high-fat/high-fructose diet, showing liver and skeletal muscle dysfunction correlates with specific fatty acid redistribution in phosphatidylcholine.

Translational and HIF1α-dependent metabolic reprograming underpin oncometabolomeplasticity and synergy between oncogenic kinase inhibitors and biguanides.

This study identifies translational reprogramming of non-essential amino acid synthesis and HIF1-dependent reductive glutamine metabolism as key factors enabling synergy between kinase inhibitors and biguanides in cancer cells.