Author

S. McLaughlan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

I. Topisirovic· 2 shared O. Larsson· 2 shared A. Saric· 1 shared C. Greenwood· 1 shared C. Oertlin· 1 shared D. Avizonis· 1 shared G. Bridon· 1 shared J. Diaz· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

I. Topisirovic

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation

V. E. B. Hipolito, J. Diaz, K. Tandoc, C. Oertlin, J. Ristau, N. Chauhan, A. Saric, S. McLaughlan, O. Larsson, I. Topisirovic, R. Botelho

This study identifies mTORC1-dependent translation as a mechanism for endo-lysosome expansion and antigen presentation during phagocyte activation.

bioRxiv · Nov 13, 2019Cell Biology

Translational and HIF1α-dependent metabolic reprograming underpin oncometabolomeplasticity and synergy between oncogenic kinase inhibitors and biguanides.

L. Hulea, S.-P. Gravel, M. Morita, M. Cargnello, O. Uchenunu, Y. K. Im, S. McLaughlan, O. Larsson, M. Ohh, T. Ferreira, C. Greenwood, G. Bridon, D. Avizonis, J. Ursini-Siegel, J. St-Pierre, , I. Topisirovic

This study identifies translational reprogramming of non-essential amino acid synthesis and HIF1-dependent reductive glutamine metabolism as key factors enabling synergy between kinase inhibitors and biguanides in cancer cells.

bioRxiv · Jul 8, 2017Cancer Biology