Author

T. Golos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:non-human primate· 3 Assay:bulk RNA-seq· 2 Organism:rat· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

H. A. Simmons· 2 shared H. Jones· 2 shared J. Schmidt· 2 shared M. L. Schotzko· 2 shared A. Kumar· 1 shared A. M. Hugon· 1 shared B. Bowman· 1 shared B. Davenport· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersPhysiology

H. A. Simmons

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Nanoparticle-mediated delivery of placental gene therapy via uterine artery catheterization in a pregnant rhesus macaque

J. Schmidt, R. Wilson, B. Davenport, T. Hacker, C. Fitz, H. A. Simmons, M. L. Schotzko, T. Golos, H. Jones

This study delivers hIGF1-loaded nanoparticles to the placenta of a pregnant rhesus macaque via uterine artery catheterization, showing successful placental uptake and expression of hIGF1.

bioRxiv · Apr 10, 2024Physiology

Listeria monocytogenes infection in pregnancy macaques alters the maternal gut microbiome

A. M. Hugon, T. Golos

This study shows that Listeria monocytogenes infection during pregnancy in macaques alters gut microbiome diversity and specific taxa, contributing to adverse pregnancy outcomes.

bioRxiv · Jun 18, 2023 · PreprintMicrobiology

Maternal, placental and fetal response to a non-viral, polymeric nanoparticle gene therapy in nonhuman primates

R. L. Wilson, J. Kropp Schmidt, B. N. Davenport, E. Ren, L. T. Keding, S. Shaw, M. L. Schotzko, K. Antony, H. A. Simmons, T. Golos, H. Jones

This study evaluates maternal, placental, and fetal responses to non-viral nanoparticle-mediated IGF1 gene therapy in nonhuman primates, finding no adverse effects and placental signaling changes indicating homeostasis maintenance.

bioRxiv · Jun 16, 2023 · PreprintPhysiology

Zika virus impacts extracellular vesicle composition and cellular gene expression in macaque early gestation trophoblasts

T. Golos, L. Block, J. Schmidt, B. Bowman, G. Wiepz, M. McKeon

This study shows ZIKV infection affects trophoblast gene expression and extracellular vesicle content in macaques, suggesting EVs as potential biomarkers for placental infection.

bioRxiv · Oct 7, 2021Cell Biology

Generation of SIV resistant T cells and Macrophages from Nonhuman Primate Induced Pluripotent Stem Cells with Edited CCR5 locus

S. S. D'Souza, A. Kumar, J. Weinfurter, M. A. Park, J. Maufort, L. Tao, H. Kang, T. Golos, J. A. Thomson, M. Reynolds, I. I. Slukvin

This study generates CCR5-edited T cells and macrophages from nonhuman primate iPSCs, showing resistance to SIV replication.

bioRxiv · May 3, 2021Cell Biology