R. L. Wilson

Intervertebral Disc Elastography to Relate Shear Modulus and Relaxometry in Compression and Bending

This study relates shear modulus and relaxometry in intervertebral discs under compression and bending to assess degeneration.

Maternal, placental and fetal response to a non-viral, polymeric nanoparticle gene therapy in nonhuman primates

This study evaluates maternal, placental, and fetal responses to non-viral nanoparticle-mediated IGF1 gene therapy in nonhuman primates, finding no adverse effects and placental signaling changes indicating homeostasis maintenance.

Insulin-like growth factor 1 signaling in the placenta requires endothelial nitric oxide synthase to support trophoblast function and normal fetal growth

This study shows that endothelial nitric oxide synthase is required for IGF1 signaling in placenta cells to support fetal growth, as IGF1 gene therapy failed to restore growth in eNOS-deficient mice.

Placental and fetal characteristics of the Ohia mouse line recapitulate outcomes in human hypoplastic left heart syndrome

The paper examines placental and fetal characteristics in the Ohia mouse model of hypoplastic left heart syndrome, finding reduced placental vascularization and altered nutrient transporter expression linked to fetal growth abnormalities.

A novel human enteroid-anaerobe co-culture system to study microbial-host interaction under physiological hypoxia

This paper introduces a co-culture system to study host-microbe interactions under physiological hypoxia using human intestinal enteroids and anaerobic bacteria.