T. H. Pers

A single cell atlas of human and mouse white adipose tissue

This study creates single-cell atlases of human and mouse white adipose tissue, identifying cell types and their roles in metabolic disease across different body weights and diets.

High-dimensional profiling demonstrates complexity, tissue imprinting, and lineage-specific precursors within the mononuclear phagocyte compartment of the human intestine

The paper uses single-cell methods to explore the complexity of the mononuclear phagocyte compartment in the human intestinal lamina propria, identifying distinct subsets, site-specific signatures, and lineage-specific precursors.

Human skeletal muscle CD90+ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetes patients

This study identifies CD90+ fibro-adipogenic progenitors in T2DM skeletal muscle and shows PDGF signaling drives their pathogenic behavior, which is mitigated by Metformin.