Author

T. J. Lu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Approach:biophysical modeling· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Approach:mechanistic / dynamical model· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

F. Xu· 2 shared G. M. Genin· 2 shared A. Isomursu· 1 shared B. Fuller· 1 shared C. Bo· 1 shared D. J. Odde· 1 shared F. Liu· 1 shared G. Huang· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiophysics

F. Xu

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2 papers

Recent·Most cited

Transient K+ current explains cross-species differences in the effects of myofibroblasts on myocytes

F. Liu, H. Wu, X. Yang, Y. Dong, G. Huang, G. M. Genin, T. J. Lu, F. Xu

The paper develops a mathematical model to explain cross-species differences in myofibroblast effects on cardiomyocytes, identifying transient K+ currents as a key factor.

bioRxiv · Nov 2, 2020 · PreprintBiophysics

Negative durotaxis: cell movement toward softer environments

A. Isomursu, K.-Y. Park, J. Hou, C. Bo, G. Shamsan, B. Fuller, J. Kasim, M. M. Mahmoodi, T. J. Lu, G. M. Genin, F. Xu, M. Lin, M. Distefano, J. Ivaska, D. J. Odde

The paper identifies negative durotaxis, where cells migrate toward softer environments, and shows that integrin adhesion and motor-clutch dynamics drive this behavior in glioblastoma and neurites.

bioRxiv · Oct 27, 2020 · PreprintBiophysics