Author

T. J. Sarkar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. Colville· 1 shared C. M. Tran· 1 shared C. R. Chu· 1 shared L. Doan· 1 shared M. Quarta· 1 shared N. Bhutani· 1 shared P. Paine· 1 shared S. Horvath· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

A. Colville

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Author profile →

2 papers

Recent·Most cited

On the Aging and Reproductive Consequences of Biological Complexity

T. J. Sarkar

This paper proposes a new theoretical model of aging that incorporates complex systems dynamics to address both the how and why of aging and reproduction.

bioRxiv · Sep 14, 2022 · PreprintBiophysics

Transient non-integrative nuclear reprogramming promotes multifaceted reversal of aging in human cells

T. J. Sarkar, M. Quarta, S. Mukherjee, A. Colville, P. Paine, L. Doan, C. M. Tran, C. R. Chu, S. Horvath, N. Bhutani, T. A. Rando, V. Sebastiano

This study shows that transient non-integrative nuclear reprogramming reverses aging in human cells by rejuvenating epigenetic clocks and cellular functions without losing identity.

bioRxiv · Mar 18, 2019Cell Biology