Author

T. K. T. Smith

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Cell Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

B. E. Kemp· 1 shared J. R. C. Nunes· 1 shared M. Cote· 1 shared M. D. Fullerton· 1 shared M. Ouimet· 1 shared N. D. LeBlond· 1 shared S. Gadde· 1 shared S. Robichaud· 1 shared

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2020-2020 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperCell Biology

B. E. Kemp

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1 paper

Recent·Most cited

Foam cell induction activates AMPK but uncouples its regulation of autophagy and lysosomal homeostasis

N. D. LeBlond, J. R. C. Nunes, T. K. T. Smith, S. Robichaud, S. Gadde, M. Cote, B. E. Kemp, M. Ouimet, M. D. Fullerton

This study shows that AMPK activation in foam cells disrupts lysosomal homeostasis despite maintaining basal AMPK signaling, suggesting a loss of AMPK's regulatory capacity in atherosclerosis.

bioRxiv · Aug 13, 2020Cell Biology