Rationally designed immunogens enable immune focusing to the SARS-CoV-2 receptor binding motif
B. M. Hauser, M. Sangesland, K. J. St. Denis, I. W. Windsor, J. Feldman, E. C. Lam, T. Kannegieter, A. B. Balazs, D. Lingwood, A. G. Schmidt
This study designs immunogens that focus immune responses to the SARS-CoV-2 receptor binding motif, enhancing neutralizing antibody breadth against related sarbecoviruses.
bioRxiv · Mar 15, 2021 · PreprintImmunology