Author
T. Kapoor
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2018-2023 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 14 mutual co-author links5 papers
Recent·Most cited
Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex
J. Chen, B. Malone, E. Llewellyn, M. Grasso, P. M. M. Shelton, P. D. B. Olinares, K. Maruthi, E. T. Eng, H. Vatandaslar, B. Chait, T. Kapoor, S. A. Darst, E. A. Campbell
The paper presents cryo-EM structures of the SARS-CoV-2 holo-RdRp complex with nsp13 helicase, revealing interactions and a new therapeutic target.
Cell · Sep 1, 2020Peer-reviewedBiophysics
Nanoscale indentation of plasma membrane establishes a contractile actomyosin scaffold through selective activation of the Amphiphysin-Rho1-Dia/DAAM and Rok pathway
T. Kapoor, P. Dubey, S. Shirolikar, K. Ray
The paper shows that nanoscale stretching of the plasma membrane recruits Amphiphysin and Rho1, leading to actomyosin scaffold formation that clamps spermatid heads.
bioRxiv · Aug 4, 2020Cell Biology
A Combination of Two Human Monoclonal Antibodies Limits Fetal Damage by Zika Virus in Macaques
K. K. A. Van Rompay, L. L. Coffey, T. Kapoor, A. Gazumyan, R. I. Keesler, A. Jurado, A. Peace, M. Agudelo, J. Watanabe, J. Usachenko, A. Singapuri, R. Immareddy, A. Ardeshir, J. B. Stuart, S. Bournazos, , D. F. Robbiani
This study shows that two Fc-modified monoclonal antibodies limit fetal neurologic damage and vertical transmission of ZIKV in pregnant macaques.
bioRxiv · Jan 31, 2020Immunology
Atypical septate junctions maintain the somatic enclosure around maturing spermatids and prevent premature sperm release in Drosophila testis.
P. Dubey, T. Kapoor, S. Gupta, S. Shirolikar, K. Ray
The paper shows that septate junctions maintain the somatic enclosure around maturing spermatids in Drosophila testis, preventing premature sperm release and ensuring proper fertility.
bioRxiv · Jul 1, 2018Cell Biology