Author

C. Gavino

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

S. Gruenheid· 3 shared A. R. Gilliland· 2 shared T. L. Raivio· 2 shared A. Kazanova· 1 shared A. MacDonald· 1 shared H. Bessaiah· 1 shared H. M. McBride· 1 shared J. A. Stratton· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersMicrobiology

S. Gruenheid

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Author profile →

3 papers

Recent·Most cited

Modeling gene-environment interactions in Parkinson's Disease: Helicobacter pylori infection of Pink1-/- mice induces CD8 T cell-dependent motor and cognitive dysfunction.

A. Kazanova, J. Sung, N. L. Oliveira, C. Gavino, H. Bessaiah, J. Pei, L. Burns, W. Miller, M. Brouillard-Galipeau, L. Zhu, L. M. Guerra, M. N. Elemeery, S. J. Recinto, A. MacDonald, J. Lanoix, , S. Gruenheid

This study shows that Helicobacter pylori infection in Pink1-/- mice causes motor and cognitive dysfunction linked to CD8 T cell activity, mimicking early PD features.

bioRxiv · Feb 25, 2024 · PreprintImmunology

Simulated colonic fluid replicates the in vivo growth capabilities of Citrobacter rodentium cpxRA mutants and uncovers additive effects of Cpx regulated genes on fitness

A. R. Gilliland, C. Gavino, S. Gruenheid, T. L. Raivio

This study shows that C. rodentium cpxRA mutants have reduced colonization and virulence in mice, mirroring their growth defects in simulated colonic fluid, suggesting that multiple Cpx-regulated genes collectively impact fitness.

bioRxiv · Aug 5, 2022Microbiology

Simulated colonic fluid replicates the in vivo growth capabilities of Citrobacter rodentium mutants and highlights a critical role for the Cpx envelope stress response in mediating stressors encountered in the gastrointestinal tract

A. R. Gilliland, C. Gavino, S. Gruenheid, T. L. Raivio

The paper shows that Cpx envelope stress response mutants of Citrobacter rodentium have growth defects in simulated colonic fluid and reduced virulence in mice.

bioRxiv · Dec 13, 2021 · PreprintMicrobiology