Metabolic intervention by low carbohydrate diet suppresses the onset and progression of neuroendocrine tumor
Y. Chen, T. Yamamoto, Y. Takahashi, T. Moro, T. Tajima, Y. Sakaguchi, N. Sakata, A. Yokoyama, S. Hijioka, A. Sada, Y. Tabata, R. Ohki
A low carbohydrate diet suppresses neuroendocrine tumor onset and progression by reducing insulin signaling and PI3K-Akt-mTOR pathway activity in mouse models and correlates with better prognosis in patients.
bioRxiv · Oct 21, 2022 · PreprintCancer Biology