Author

T. Purnell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

K. E. Hargrave· 3 shared M. K. MacLeod· 3 shared J. C. Worrell· 2 shared A. Masdefiol Garriga· 1 shared C. Pirillo· 1 shared D. Todd· 1 shared E. Brennan· 1 shared E. T. Chimbayo· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersImmunology

K. E. Hargrave

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Lung influenza virus specific memory CD4 T cell location and optimal cytokine production are dependent on interactions with lung antigen-presenting cells

K. E. Hargrave, J. C. Worrell, C. Pirillo, E. Brennan, A. Masdefiol Garriga, J. I. Gray, T. Purnell, E. W. Roberts, M. K. MacLeod

bioRxiv · Sep 19, 2023Immunology

Triphasic production of IFNγ by innate and adaptive lymphocytes following influenza A virus infection

G. E. Finney, K. E. Hargrave, M. Pingen, T. Purnell, D. Todd, F. MacDonald, J. C. Worrell, M. K. MacLeod

This study identifies a triphasic production of IFNγ by different immune cell types during and after influenza A virus infection, highlighting memory-like phenotypes in some cells.

bioRxiv · May 23, 2023Immunology

Enhanced survival and low proliferation marks multifunctional virus specific memory CD4 T cells

L. M. Westerhof, J. Noonan, K. E. Hargrave, E. T. Chimbayo, Z. Cheng, T. Purnell, M. R. Jackson, N. Borcherding, M. K. MacLeod

The paper identifies multifunctional virus-specific memory CD4 T cells that exhibit enhanced survival and low proliferation, suggesting survival, not proliferation, drives their persistence in the memory pool.

bioRxiv · Dec 13, 2022 · PreprintImmunology