Author

T. Raisch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 2

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 4 Approach:experimental assay· 3 Organism:human· 2 Research Focus:protein structure prediction· 2 Research Focus:benchmarking· 1 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

S. Raunser· 4 shared A. Musacchio· 2 shared D. Prumbaum· 2 shared F. Merino· 2 shared I. R. Vetter· 2 shared A. Apelbaum· 1 shared B. Siebolds· 1 shared C. Antoni· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersBiophysics

S. Raunser

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4 papers

Recent·Most cited

Cryo-EM structure of Slo1 with the auxiliary γ1 subunit suggests mechanism of depolarization-independent activation

M. Redhardt, S. Raunser, T. Raisch

The paper presents a cryo-EM structure of Slo1 with the γ1 subunit, revealing how γ1 stabilizes the active conformation of the voltage-sensor domain and suggests a mechanism for depolarization-independent activation.

bioRxiv · Nov 1, 2023 · PreprintBiophysics

Structure of the human inner kinetochore CCAN complex and its significance for human centromere organization

M. E. Pesenti, T. Raisch, D. Conti, I. Hoffmann, D. Vogt, D. Prumbaum, I. R. Vetter, S. Raunser, A. Musacchio

The paper reports a cryo-EM structure of the human CCAN complex and discusses its implications for CENP-A nucleosome recognition and centromere organization.

bioRxiv · Jan 6, 2022Biochemistry

Structure of the RZZ complex and molecular basis of Spindly-driven corona assembly at human kinetochores

T. Raisch, G. Ciossani, E. d'Amico, V. Cmentowski, S. Carmignani, S. Maffini, F. Merino, S. Wohlgemuth, I. R. Vetter, S. Raunser, A. Musacchio

The paper reports the structure of the RZZ complex and demonstrates the molecular mechanism of corona assembly at human kinetochores using cryo-EM and in vitro assays.

bioRxiv · Dec 3, 2021Biochemistry

SPHIRE-crYOLO: A fast and accurate fully automated particle picker for cryo-EM

T. Wagner, F. Merino, M. Stabrin, T. Moriya, C. Antoni, A. Apelbaum, P. Hagel, O. Sitsel, T. Raisch, D. Prumbaum, D. Quentin, D. Roderer, S. Tacke, B. Siebolds, E. Schubert, , S. Raunser

The paper introduces crYOLO, a deep learning-based particle picker for cryo-EM that achieves high accuracy and speed, enabling automated data pre-processing.

bioRxiv · Mar 13, 2019Biophysics