Author

T. Sabedot

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

H. Noushmehr· 2 shared A. D. Berezovsky· 1 shared A. deCarvalho· 1 shared A. Font-Tello· 1 shared A. Gusev· 1 shared B. J. Abraham· 1 shared B. Y. Karlan· 1 shared C. Mueller· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

H. Noushmehr

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2 papers

Recent·Most cited

Impact of genomic background and developmental state on signaling pathways and response to therapy in Glioblastoma patient-derived cells

A. D. Berezovsky, O. Nuga, I. Datta, K. Bergman, T. Sabedot, K. Gurdziel, S. Irtenkauf, L. Hasselbach, Y. Meng, C. Mueller, E. Petricoin, S. Brown, N. Purandare, S. Aras, T. Mikkelsen, , A. deCarvalho

This study examines how genomic background and developmental state affect signaling pathways and therapy response in GBM patient-derived cells, finding that differentiation increases TMZ resistance and activates DNA-damage interferon responses.

bioRxiv · Mar 14, 2024 · PreprintCancer Biology

Predicting master transcription factors from pan-cancer expression data

J. Reddy, M. A. S. Fonseca, R. I. Corona, R. Nameki, F. Segato Dezem, I. A. Klein, H. Chang, D. Chaves-Moreira, L. Afeyan, T. M. Malta, X. Lin, F. Abbasi, A. Font-Tello, T. Sabedot, P. Cejas, , K. Lawrenson

This paper introduces CaCTS, an algorithm that identifies candidate master transcription factors (MTFs) across 34 cancer types using RNA-seq data, revealing novel MTFs and functional groupings.

bioRxiv · Nov 12, 2019Cancer Biology