Author

T. Sandoval

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

C. Nikopoulou· 2 shared P. Tessarz· 2 shared S. Parekh· 2 shared A. J. Vesting· 1 shared A. Pouikli· 1 shared A. Tresch· 1 shared A.-L. Schumacher· 1 shared C. Mylonas· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

C. Nikopoulou

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2 papers

Recent·Most cited

Hypoxia promotes osteogenesis via regulation of the mito-nuclear communication

A. Pouikli, M. Maleszewska, S. Parekh, C. Nikopoulou, J.-J. Bonfiglio, C. Mylonas, T. Sandoval, A.-L. Schumacher, Y. Hinze, I. Matic, P. Tessarz

This study shows that high oxygen levels impair osteogenesis in MSCs by disrupting mito-nuclear communication through chromatin compaction and histone hypo-acetylation, which can be reversed by acetate supplementation.

bioRxiv · Feb 26, 2022 · PreprintCell Biology

Single-cell resolution unravels spatial alterations in metabolism, transcriptome and epigenome of ageing liver

C. Nikopoulou, N. Kleinenkuhnen, S. Parekh, T. Sandoval, F. Schneider, P. Giavalisco, M. Bozukova, A. J. Vesting, J. Altmueller, T. Wunderlich, V. Kondylis, A. Tresch, P. Tessarz

The paper investigates age-related spatial changes in metabolism, transcriptome, and epigenome in the murine liver using multi-omics approaches.

bioRxiv · Dec 14, 2021 · PreprintCell Biology