T. Shichita

Sustaining microglial reparative function enhances stroke recovery

This study identifies ZFP384 as a regulator that impairs microglial reparative function after stroke, and shows that targeting ZFP384 enhances recovery even in the chronic phase.

Extracellular DJ-1 induces sterile inflammation in the ischemic brain

This paper shows that extracellular DJ-1 triggers inflammation in ischemic brains by activating TLR2 and TLR4, and that blocking DJ-1 reduces inflammation and neuronal damage.