Author

J. E. Teixeira

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Organism:chicken / avian· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

C. D. Huston· 3 shared D. W. Griggs· 2 shared E. E. Stebbins· 2 shared M. M. Hasan· 2 shared A. C. Cameron· 1 shared A. Mushtaq· 1 shared A. Sateriale· 1 shared C. E. Klopfer· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersMicrobiology

C. D. Huston

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cryptosporidium Life Cycle Small Molecule Probing Implicates Translational Repression And An Apetala 2 Transcription Factor In Sexual Differentiation

M. M. Hasan, E. B. Mattice, J. E. Teixeira, R. S. Jumani, E. E. Stebbins, C. E. Klopfer, S. E. Franco, M. S. Love, C. W. McNamara, C. D. Huston

This study identifies small-molecule compounds that modulate sexual differentiation in Cryptosporidium using a multi-readout imaging assay and confirms translational repression and an AP2 transcription factor's role in this process.

bioRxiv · Dec 18, 2023 · PreprintMicrobiology

Identification of potent and orally efficacious phosphodiesterase inhibitors in Cryptosporidium parvum-infected immunocompromised mice

J. E. Teixeira, M. Gasonoo, P. Miller, J. Ajiboye, A. C. Cameron, E. Stebbins, S. D. Campbell, D. W. Griggs, T. Spangenberg, M. J. Meyers, C. D. Huston

This study identifies potent PDE-V inhibitors effective against Cryptosporidium parvum in immunocompromised mice, with minimal off-target effects.

bioRxiv · Sep 26, 2023 · PreprintMicrobiology

Spontaneous selection of Cryptosporidium drug resistance in a calf model of infection

M. M. Hasan, E. E. Stebbins, R. K. M. Choy, J. R. Gillespie, E. de Hostos, P. J. Miller, A. Mushtaq, R. M. Ranade, J. E. Teixeira, C. L. M. J. Verlinde, A. Sateriale, Z. Zhang, D. M. Osbourn, D. W. Griggs, E. Fan, , C. D. Huston

This study reports the spontaneous emergence of drug resistance in Cryptosporidium parvum infected calves treated with a methionyl-tRNA synthetase inhibitor, highlighting the potential for anticryptosporidial resistance.

bioRxiv · Jan 4, 2021Microbiology