Author

T. Umehara

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:bulk RNA-seq· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

M. Kikuchi· 2 shared M. Wakamori· 2 shared A. K. Aragaki· 1 shared H. D. Wu· 1 shared H. Nakamura· 1 shared K. Okabe· 1 shared K. Ura· 1 shared M. Awad· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersBiochemistry

M. Kikuchi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Testosterone-Induced Metabolic Changes in Seminal Vesicle Epithelial cells Alter Plasma Components to Enhance Sperm Motility

T. Yamanaka, Z. Xiao, N. Tsujita, M. Awad, T. Umehara, M. Shimada

This study identifies testosterone-induced metabolic changes in seminal vesicle epithelial cells that enhance sperm motility through fatty acid synthesis.

bioRxiv · Jan 16, 2024Cell Biology

Epigenetic mechanisms to propagate histone acetylation by p300/CBP

M. Kikuchi, S. Morita, M. Wakamori, S. Sato, T. Uchikubo-Kamo, M. Shirouzu, T. Umehara

This study identifies how p300/CBP reads and writes histone acetylation to propagate epigenetic marks and activate gene transcription.

bioRxiv · Mar 31, 2023Biochemistry

Quantification of the effect of site-specific histone acetylation on chromatin transcription rate

M. Wakamori, K. Okabe, K. Ura, T. Funatsu, M. Takinoue, T. Umehara

The paper quantifies how specific histone H4 acetylation sites affect chromatin transcription rates using a reconstituted system and kinetic modeling.

bioRxiv · Oct 15, 2020Biophysics

Rational design and implementation of a chemically inducible hetero-trimerization system

H. D. Wu, M. Kikuchi, O. Dagliyan, A. K. Aragaki, H. Nakamura, N. V. Dokholyan, T. Umehara, T. Inoue

This paper designs a chemically inducible trimerization system by splitting FRB and FKBP, enabling precise control of tri-organellar junctions and membrane lipid perturbations in live cells.

bioRxiv · Mar 16, 2020Cell Biology