Author

T. Valenta

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

K. Basler· 3 shared A. E. Moor· 2 shared C. Borrelli· 2 shared G. Hausmann· 2 shared K. Handler· 2 shared A. Gurtner· 1 shared A. Lafzi· 1 shared B. Becher· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersCell Biology

K. Basler

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Terminal differentiation of villus-tip enterocytes is governed by distinct members of Tgfβ superfamily

L. Berkova, H. Fazilaty, Q. Yang, J. Kubovciak, M. Stastna, D. Hrckulak, M. Vojtechova, M. D. Brugger, G. Hausmann, P. Liberali, V. Korinek, K. Basler, T. Valenta

This study identifies distinct roles of Bmp2 and Tgfβ in driving specific enterocytic programs at different villus regions, with Bmp2 promoting terminal differentiation at the villus-tip.

bioRxiv · Nov 11, 2022Cell Biology

Single-cell RNA sequencing unveils intestinal eosinophil development and specialization

A. Gurtner, C. Borrelli, N. G. Nunez, I. Gonzalez-Perez, D. Crepaz, K. Handler, T. Valenta, K. Basler, B. Becher, A. E. Moor, I. C. Arnold

The paper uses single-cell transcriptomics and flow cytometry to identify five eosinophil subsets in mice, revealing their developmental stages and specialized functions in the GI tract.

bioRxiv · Oct 27, 2021Immunology

Discrete regulation of b-catenin-mediated transcription governs identity of intestinal epithelial stem cells

C. Borrelli, T. Valenta, K. Handler, K. Velez, G. Moro, A. Lafzi, L. de Vargas Roditi, G. Hausmann, A. E. Moor, K. Basler

This study shows that discrete regulation of β-catenin-mediated transcription by co-factors determines the identity and proliferative behavior of intestinal epithelial stem cells.

bioRxiv · May 19, 2020 · PreprintCell Biology