T. Wilkinson

Robust prediction of relative binding energies for protein-protein complex mutations using free energy perturbation calculations

The paper benchmarks free energy perturbation calculations for predicting mutation effects on protein-protein binding affinity and introduces an automated method to improve accuracy.

Beehives possess their own distinct microbiomes

This study analyzes the bacterial diversity in honey and beebread from 15 beehives, revealing distinct microbiomes influenced by local plants and environmental factors.

Immunopeptidomic analysis of influenza A virus infected human tissues identifies internal proteins as a rich source of HLA ligands

Association between vitamin D deficiency and exercise capacity in patients with CKD, a cross-sectional analysis

This study examines the relationship between vitamin D deficiency and exercise capacity in CKD patients, finding no strong link to muscle size but a possible role in reduced exercise capacity.

In silico identification of novel peptides with antibacterial activity against multidrug resistant Staphylococcus aureus

This study identifies two novel antimicrobial peptides, HG2 and HG4, effective against multidrug-resistant Staphylococcus aureus using in silico methods and experimental validation.

Islands in the desert: Environmental distribution modelling of endemic flora reveals the extent of Pleistocene tropical relict vegetation in southern Arabia

The paper models environmental distribution of endemic plants in southern Arabia to identify a Pleistocene climate refugium in the Central Desert of Oman.

Adherence to the iDSI reference case among published cost-per-DALY averted studies

This study evaluates adherence to the iDSI reference case guidelines in cost-per-DALY averted studies from 2011 to 2017, finding improved reporting standards but no significant methodological improvement.

The rumen microbiome: an underexplored resource for novel antimicrobial discovery

The paper identifies novel antimicrobial peptides from the rumen microbiome and demonstrates their efficacy against MRSA in vitro and in a mouse model.