P. Skipp

Immunopeptidomics-guided identification of functional neoantigens in non-small cell lung cancer

The paper identifies functional neoantigens in NSCLC patients using immunopeptidomics, achieving an 83% success rate in eliciting immune responses.

Integrative transcriptomic and proteomic meta-analysis of Zika viral infection reveals potential mechanisms for oncolytic therapy in neuroblastoma

This study identifies molecular mechanisms of Zika virus-induced oncolysis in neuroblastoma and highlights a promising oncolytic virotherapy candidate.

Identification of neoantigens in esophageal adenocarcinoma

This study identifies neoantigens in esophageal adenocarcinoma, finding one directly presented HLA-I neoantigen and a predicted HLA-II neoantigen with T-cell responses, highlighting challenges in neoantigen detection.

Immunopeptidomic analysis of influenza A virus infected human tissues identifies internal proteins as a rich source of HLA ligands

Annexin A1 is a polarity cue that directs planar mitotic spindle orientation during mammalian epithelial morphogenesis

This study identifies Annexin A1 as a polarity cue that directs planar mitotic spindle orientation in mammalian epithelial cells by regulating LGN and NuMA cortical anchoring.

Proteomic characterization of GSK3β knockout shows altered cell adhesion and metabolic pathway utilisation in colorectal cancer cells

This study uses proteomic analysis of GSK3β knockout colorectal cancer cells to identify altered cell adhesion and metabolic pathways.

Deep proteomic analysis of Dnmt1 mutant/hypomorphic colorectal cancer cells reveals dys-regulation of Epithelial-Mesenchymal Transition and subcellular re-localization of Beta-Catenin

This study performs a proteomic analysis of Dnmt1 hypomorph colorectal cancer cells, revealing dysregulation of EMT and subcellular relocalization of Beta-Catenin.