Polyphosphate uses mTOR, pyrophosphate, and Rho GTPase components to potentiate bacterial survival in Dictyostelium
R. J. Rahman, R. Rijal, S. Jing, T.-A. Chen, I. Ismail, R. H. Gomer
This paper identifies key components of the polyP signaling pathway in D. discoideum that inhibit bacterial killing, suggesting potential therapeutic targets for enhancing macrophage pathogen clearance.
bioRxiv · May 3, 2023 · PreprintMicrobiology