Author

T.-X. Tang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

D. G. S. Capelluto· 2 shared A. Biscardi· 1 shared A. Karcini· 1 shared A. M. Brown· 1 shared C. J. Gottschalk· 1 shared C. V. Finkielstein· 1 shared E. Littleton· 1 shared I. M. Lazar· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

D. G. S. Capelluto

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2 papers

Recent·Most cited

Structural, in silico, and functional analysis of a Disabled-2-derived peptide for recognition of sulfatides

W. Song, C. J. Gottschalk, T.-X. Tang, A. Biscardi, J. F. Ellena, C. V. Finkielstein, A. M. Brown, D. G. S. Capelluto

This study identifies critical residues in a Dab2-derived peptide that bind sulfatides and inhibit platelet aggregation.

bioRxiv · May 6, 2020Biophysics

Preferential phosphatidylinositol 5-phosphate binding contributes to a destabilization of the VHS domain structure of Tom1

W. Xiong, T.-X. Tang, E. Littleton, A. Karcini, I. M. Lazar, D. G. S. Capelluto

This study shows that PtdIns5P binding destabilizes the Tom1 VHS domain structure, affecting its function and contributing to bacterial survival during Shigella infection.

bioRxiv · Jun 14, 2019Biophysics