Spinophilin limits metabotropic glutamate receptor 5 scaffolding to the postsynaptic density and cell type-specifically mediates excessive grooming
Cameron W. Morris, Darryl S. Watkins, Nikhil R. Shah, Taylor Pennington, Basant Hens, Guihong D. Qi, Emma H. Doud, Amber L. Mosley, Brady K. Atwood, Anthony J. Baucum
The paper investigates the role of spinophilin in mediating mGluR5-dependent repetitive motor dysfunction in striatal neurons, showing subtype-specific effects on grooming behavior and synaptic plasticity.
Biological Psychiatry · Dec 13, 2022Peer-reviewedNeuroscience