Author

Basant Hens

Indiana University School of MedicineORCID 0000-0002-1139-8312Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Anthony J. BaucumiD· 3 shared Emma H. DoudiD· 3 shared Amber L. MosleyiD· 2 shared Brady K. AtwoodiD· 2 shared Cameron W. MorrisiD· 2 shared Nikhil R. ShahiD· 2 shared Darryl S. WatkinsiD· 1 shared Emily T. Claeboe· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersNeuroscience

Anthony J. BaucumORCID

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3 papers

Recent·Most cited

NeuroscienceJournal of Pharmacology and Experimental TherapeuticsPeer-reviewedDec 4, 2025

Striatal spinophilin enhances D2R interaction with cytosolic proteins to mediate persistent D2R agonist-induced locomotor suppression.

Basant Hens, Whitney R. Smith-Kinnaman, Emma H. Doud, Anthony J. Baucum

This study shows that spinophilin enhances D2R interaction with cytosolic proteins, contributing to D2R agonist-induced locomotor suppression in Parkinson's disease.

1 citation

mouseexperimental assay

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NeurosciencebioRxivPreprintJan 23, 2025

Proximity labeling and orthogonal nanobody pulldown (ID-oPD) approaches to map the spinophilin interactome uncover a putative role for spinophilin in protein homeostasis.

Emily T. Claeboe, Keyana L. Blake, Nikhil R. Shah…·Anthony J. Baucum

The paper uses ID-oPD to map spinophilin's interactome, identifying proteins involved in mRNA processing and translation, and suggests a role in synaptic protein expression.

2 citations

humanproteomics

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NeuroscienceBiological PsychiatryPeer-reviewedDec 13, 2022

Spinophilin limits metabotropic glutamate receptor 5 scaffolding to the postsynaptic density and cell type-specifically mediates excessive grooming

Cameron W. Morris, Darryl S. Watkins, Nikhil R. Shah…·Anthony J. Baucum

The paper investigates the role of spinophilin in mediating mGluR5-dependent repetitive motor dysfunction in striatal neurons, showing subtype-specific effects on grooming behavior and synaptic plasticity.

12 citations

mouseexperimental assay

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