Author

Teri Sakshaug

Norwegian University of Science and Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2

Frequent Co-Authors

Katja ScheffleriD· 4 shared Magnar BjøråsiD· 4 shared Andreas AbentungiD· 3 shared Tobias Obermann· 2 shared Ana B. Nunez-NescolardeiD· 1 shared Antonio Sarno· 1 shared Catarina Damião· 1 shared Junbai WangiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersNeuroscience

Katja SchefflerORCID

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4 papers

Recent·Most cited

Ogg1 regulates context-dependent glial states in Alzheimer's disease

Andreas Abentung, Teri Sakshaug, Paulina Schnur, Milena Egiazarian, Catarina Damião, Karoline Aakre, Tobias Obermann, Mirta Sousa, Nicolas Kunath, Magnar Bjørås, Katja Scheffler

This study shows Ogg1 has opposing effects on glial states in Alzheimer's disease, improving memory and reducing amyloid burden in a mouse model while impairing memory under physiological conditions.

bioRxiv · Nov 9, 2026 · PreprintNeuroscience

Genomic 8-oxoguanine modulates gene transcription independent of its repair by DNA glycosylases OGG1 and MUTYH

Tobias Obermann, Teri Sakshaug, Vishnu Vignesh Kanagaraj, Andreas Abentung, Mirta Mittelstedt Leal de Sousa, Lars Hagen, Antonio Sarno, Magnar Bjørås, Katja Scheffler

The paper investigates the role of 8-oxoguanine (OG) in gene transcription, showing that OG accumulation in promoter regions correlates with metabolic and damage response gene expression, independent of repair by OGG1 and MUTYH.

Redox Biology · Dec 5, 2024Peer-reviewedGenomics

DNA glycosylases Ogg1 and Mutyh mediate gene expression of PRC2 target genes important for neuronal processes underlying memory formation

Andreas Abentung, Teri Sakshaug, Rabina Dumaru, Nina‐Beate Liabakk, Mingyi Yang, Junbai Wang, Magnar Bjørås, Katja Scheffler

This study shows that DNA glycosylases Ogg1 and Mutyh regulate gene expression of PRC2 target genes, affecting memory formation through epigenetic remodeling in the brain.

bioRxiv · Apr 16, 2024 · PreprintNeuroscience

Age- and sex-dependent effects of DNA glycosylase Neil3 on amyloid pathology, adult neurogenesis, and memory in a mouse model of Alzheimer's disease

Milena A. Egiazarian, Silje Strømstad, Teri Sakshaug, Ana B. Nunez-Nescolarde, Nicole Bethge, Magnar Bjørås, Katja Scheffler

This study investigates the role of Neil3 in Alzheimer's disease progression, finding age- and sex-dependent effects on amyloid pathology and memory in a mouse model.

Free Radical Biology and Medicine · Nov 1, 2022Peer-reviewedNeuroscience