Author

Tobias Obermann

Norwegian University of Science and Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Organism:mouse· 1

Frequent Co-Authors

Magnar BjøråsiD· 3 shared Andreas AbentungiD· 2 shared Katja ScheffleriD· 2 shared Teri Sakshaug· 2 shared Alessia BellinaiD· 1 shared Andreas Gjosaether· 1 shared Antonella VirgilioiD· 1 shared Antonio Sarno· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersNeuroscience

Magnar BjøråsORCID

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3 papers

Recent·Most cited

Ogg1 regulates context-dependent glial states in Alzheimer's disease

Andreas Abentung, Teri Sakshaug, Paulina Schnur, Milena Egiazarian, Catarina Damião, Karoline Aakre, Tobias Obermann, Mirta Sousa, Nicolas Kunath, Magnar Bjørås, Katja Scheffler

This study shows Ogg1 has opposing effects on glial states in Alzheimer's disease, improving memory and reducing amyloid burden in a mouse model while impairing memory under physiological conditions.

bioRxiv · Nov 9, 2026 · PreprintNeuroscience

Apurinic/apyrimidinic endodeoxyribonuclease 1 contributes to the repair of damaged intercalated-motif of telomeric sequences

Alessia Bellina, Matilde Clarissa Malfatti, Tobias Obermann, Kayla Grooms, Andreas Gjosaether, Zahraa Othman, Gilmar F. J. Salgado, Daniela Marasco, Antonella Virgilio, Veronica Esposito, Giulia Antoniali, Catia Mio, Matteo Pivetta, Magnar Bjørås, Barbara van Loon, Gianluca Tell

This study investigates APE1's role in repairing damaged telomeric i-motif structures and its interaction with PCBP1 in maintaining telomere integrity.

bioRxiv · Dec 18, 2025 · PreprintMolecular Biology

Genomic 8-oxoguanine modulates gene transcription independent of its repair by DNA glycosylases OGG1 and MUTYH

Tobias Obermann, Teri Sakshaug, Vishnu Vignesh Kanagaraj, Andreas Abentung, Mirta Mittelstedt Leal de Sousa, Lars Hagen, Antonio Sarno, Magnar Bjørås, Katja Scheffler

The paper investigates the role of 8-oxoguanine (OG) in gene transcription, showing that OG accumulation in promoter regions correlates with metabolic and damage response gene expression, independent of repair by OGG1 and MUTYH.

Redox Biology · Dec 5, 2024Peer-reviewedGenomics