Targeting Langerhans cells using a modular mannosylated nucleic acid-based vaccine platform
Simon Christian Vinther, Antonia Resag, Khoa M. Le, Claudia Zelle‐Rieser, Helen Strandt, Mette Galsgaard Malle, Stig Hill Christiansen, Barbara Del Frari, Theresia Stigger, Bastian Schilling, Jonas Wohlfarth, Steffen Thiel, Julián Valero, Patrizia Stoitzner, Jørgen Kjems
This study develops a mannosylated nucleic acid-based vaccine platform that targets Langerhans cells in the skin, enhancing antigen presentation and T cell activation.
Journal of Controlled Release · Feb 18, 2026Peer-reviewedMolecular Biology