Mette Galsgaard Malle

This study uses single-particle tracking to compare early entry checkpoints of SARS-CoV-2 G614 and BA.5 variants, revealing variant-specific differences in binding and internalization.

This study investigates how recipient cell identity influences intracellular transport and membrane interactions of extracellular vesicles across species, finding that recipient-cell environment has a greater impact than EV origin.

This study develops a mannosylated nucleic acid-based vaccine platform that targets Langerhans cells in the skin, enhancing antigen presentation and T cell activation.

This paper describes a DNA origami needle that targets cancer cells and delivers cargo into the cytosol by mimicking bacteriophage mechanisms.

The paper identifies surface-bound RNA on extracellular vesicles and shows it is co-delivered to target cells, suggesting a new RNA uptake mechanism.

The paper evaluates the CytoFLEX Nano flow cytometer's performance for analyzing extracellular vesicles in complex biofluids.

This paper introduces a DNA origami stamping technique for precise nanoscale biomolecule patterning, validated using DNA-PAINT microscopy to assess efficiency and resolution.

This study uses single-vesicle tracking to show α-synuclein oligomers form pores through a three-stage process influenced by membrane curvature, charge, lipids, and ligands.