Bastian Schilling

This study develops a mannosylated nucleic acid-based vaccine platform that targets Langerhans cells in the skin, enhancing antigen presentation and T cell activation.

The paper identifies melanoma differentiation and immune exhaustion as predictors of tumor progression and therapy response in in-transit melanoma patients through multiomic profiling.

This study uses SILAC-based quantification to analyze how MAPK inhibitors affect the immunopeptidome in melanoma cells, identifying potential targets for immunotherapy.

The paper shows that U1 snRNP-dependent intronic polyadenylation suppresses miRNA biogenesis in melanoma by altering TRPM1 alternative polyadenylation signals.