Author

Thomas Klein

Boehringer Ingelheim (Germany)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Adriana Papadimitropoulou· 1 shared Anthony GavalasiD· 1 shared Christian StigloheriD· 1 shared Christoph ErbacheriD· 1 shared Chrysanthi Charalampous· 1 shared Diana Reinhardt· 1 shared Gareth R. WillisiD· 1 shared Ioannis SerafimidisiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

Adriana Papadimitropoulou

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Pharmacological targeting of SOS1-RAS interaction triggers pancreatic β-cell proliferation and sustainably reverses diabetic hyperglycemia

Adriana Papadimitropoulou, Chrysanthi Charalampous, Paraskevi Kogionou, Diana Reinhardt, Johanna Sonntag, Anthony Gavalas, Marco H. Hofmann, Patrik Erlmann, Michael Franti, Jonas Doerr, Thomas Klein, Gareth R. Willis, Ioannis Serafimidis

This study shows that the SOS1-RAS inhibitor BI-3406 promotes β-cell proliferation and reverses diabetic hyperglycemia in mice.

bioRxiv · Jun 3, 2025 · PreprintCell Biology

Interaction of human keratinocytes and nerve fiber terminals at the neuro-cutaneous unit

Christoph Erbacher, Sebastian Britz, Philine Dinkel, Thomas Klein, Markus Sauer, Christian Stigloher, Nurcan Üçeyler

The paper investigates the interaction between human keratinocytes and nerve fibers at the neuro-cutaneous unit using advanced imaging techniques and a co-culture system.

eLife · Dec 21, 2023Peer-reviewedNeuroscience