Cell BiologybioRxivPreprint
Pharmacological targeting of SOS1-RAS interaction triggers pancreatic β-cell proliferation and sustainably reverses diabetic hyperglycemia
Adriana Papadimitropoulou, Chrysanthi Charalampous, Paraskevi Kogionou…·Ioannis Serafimidis
This study shows that the SOS1-RAS inhibitor BI-3406 promotes β-cell proliferation and reverses diabetic hyperglycemia in mice.