Author

Gareth R. Willis

Boehringer Ingelheim (United States)ORCID 0000-0002-7302-8261Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Adriana Papadimitropoulou· 1 shared Anthony GavalasiD· 1 shared Chrysanthi Charalampous· 1 shared Diana Reinhardt· 1 shared Ioannis SerafimidisiD· 1 shared Johanna SonntagiD· 1 shared Jonas DoerriD· 1 shared Marco H. HofmanniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Adriana Papadimitropoulou

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1 paper

Recent·Most cited

Pharmacological targeting of SOS1-RAS interaction triggers pancreatic β-cell proliferation and sustainably reverses diabetic hyperglycemia

Adriana Papadimitropoulou, Chrysanthi Charalampous, Paraskevi Kogionou, Diana Reinhardt, Johanna Sonntag, Anthony Gavalas, Marco H. Hofmann, Patrik Erlmann, Michael Franti, Jonas Doerr, Thomas Klein, Gareth R. Willis, Ioannis Serafimidis

This study shows that the SOS1-RAS inhibitor BI-3406 promotes β-cell proliferation and reverses diabetic hyperglycemia in mice.

bioRxiv · Jun 3, 2025 · PreprintCell Biology